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Retinal and Macular Degeneration Clinical Research Group
The Retinal and Macular Degeneration Clinical Research Group focuses on translational and clinical research in retinal disease. Its goal is to generate the evidence base required for the development and clinical implementation of novel therapeutic strategies. Key projects and focus areas A key milestone is the EyeConic Study, a global…
Glaucoma Clinical Research Group
Glaucoma is a group of eye diseases that gradually damage the optic nerve, which connects the eye to the brain and transmits visual information. Often called the “silent thief of sight,” glaucoma typically progresses without noticeable symptoms until significant vision loss has occurred. The disease primarily affects retinal ganglion cells—specialized…
Ophthalmic Genetics Group
The ophthalmic genetics group pursues an interdisciplinary research program. The group focusses on discovering the genetic cause of monogenic and genetically complex ophthalmic disease. The research team is particularly interested in defining the mutational landscape of retinal ciliopathies, which they believe to be the most prevalent cause for hereditary blindness…
Genetic Epidemiology of Ophthalmic Diseases Group
The research themes of the genetic epidemiology of ophthalmic diseases group are the genetic causes and the epidemiology of four eye disorders: myopia, age-related macular degeneration, primary open-angle glaucoma, and retinal dystrophies. The group focuses on the identification of genetic causes of eye disorders, environmental risk factors, gene-environment interaction, phenotyping…
Ophthalmic Translational Research Group
The Ophthalmic translation group focuses on translating science and technology to the clinic. Recent advances in the understanding of genes, cell types and circuits involved in vision opened up the possibility to develop repair strategies, including gene therapy, for the loss of vision. Gene therapy for vision loss is now…
Quantitative Visual Physiology Group
The group aims to clarify how the retina transforms visual input and resulting retinal computation into eye movement, a behavioral control signal. When light falls in the mammalian eye, the incoming photons are sensed by photoreceptors in the outer retina and transduced into electric activity of neurons. Neurons process the…
Theoretical and Computational Neuroscience Group
The group focuses on a range of topics in theoretical and computational neuroscience and cognitive science. These topics, however, are tied together through a central question: How does the brain represent and manipulate information? Among the more concrete approaches to this question, the group analyses and models neural activity in…
Human Retinal and Central Visual Circuits Group
Visual circuits: structure, function, and repair Vision is a key sense for humans, and dysfunction of the visual system leads to visual handicap or blindness. The visual circuits group aims to find ways to repair visual dysfunction by investigating the function of the retina, thalamus, and cortex at the level…