Feasibility and Safety of a Coaxial Dual-Wavelength Optical Coherence Tomography Apparatus

March 16, 2026
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AUTHORS

Luca Cedro, Pascal W Hasler, Christoph Meier, Boris Povazay, Christian Burri, Matthias Mooser, Pascal Kaiser, Simon P Rothenbuehler, Philipp L Müller, Javier Zarranz-Ventura, Catherine Egan, Adnan Tufail, Hendrik P N Scholl, Peter M Maloca

Ophthalmic Res. 2021;64(1):55-61. doi: 10.1159/000508751. Epub 2020 May 19.

ABSTRACT

PURPOSE: To evaluate the feasibility and safety of a coaxial dual-wavelength optical coherence tomography (OCT) device (marked as Hydra-OCT).

METHODS: Healthy participants without ocular pathology underwent retinal imaging using the Hydra-OCT allowing for simultaneous measurement of retinal scanning of 840 and 1,072 nm wavelength. Before and after measurement, best-corrected visual acuity and patients’ comfort were assessed. Representative OCT images from both wavelengths were compared by 5 independent graders using a subjective grading scheme.

RESULTS: A total of 30 eyes of 30 participants (8 females and 22 males) with a mean age of 26.5 years (range from 19 to 55 years) were included. Dual-wavelength image acquisition was made possible in each subject. The participant’s effort and comfort assessment using the Hydra-OCT imaging revealed an equivalent value as compared to the commercially available OCT machine. No adverse events were reported, and visual acuity was not altered by the Hydra-OCT. Imaging between the systems was comparable.

CONCLUSIONS: This study provides evidence for the feasibility and safety of a coaxial dual-wavelength OCT imaging method under real-life conditions. The novel Hydra-OCT imaging device may offer additional insights into the pathology of retinal and choroidal diseases.

PMID:32428922 | DOI:10.1159/000508751

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