Researchers and Clinicians united

to restore vision.

Myopia Research Group

Head: Frank Schaeffel

During normal visual development, children’s eyes lengthen at the same speed as the focal length of the optics. The result is an optimally sharp image on the retina and best visual acuity – which most kids have developed by the time they leave kindergarten. As they grow older, however, some eyes unfortunately tend to grow more than necessary. By the time they get to high school examinations, about half of the young people in Europe may be myopic – in other words near-sighted.

The good news is that ‘common’ near-sightedness can be dealt with by spectacles or contact lenses. The bad news is that high myopia (minus 6 diopters or more) increases the risk of retinal complications. These can already cause severe visual deficits by middle age.

It is therefore important to slow the progression of myopia as early as possible.

The IOB Myopia Research Group will develop and study visual stimuli to reduce eye growth. These studies will start in human subjects, but we also plan to study the visual control of eye growth in mouse models. Our team has extensive experience in developing and using optical technologies to measure miniature changes in the eyes of humans and mice, and in the development of novel visual stimuli.

Group Members

Group Leader: Frank Schaeffel

Barbara Swiatczak -Postdoc

Léa Ingrassia - PhD student

Selected Journal Articles

Reading and Myopia: Contrast Polarity Matters

Aleman AC, Wang M, Schaeffel F.

Sci Rep. 2018 Jul 18;8(1):10840

Changes in fundus reflectivity during myopia development in chickens

Swiatczak B, Feldkaemper M, Schaeffel F.

Biomed Opt Express. 2019 Mar 13;10(4):1822-1840

Probing the Potency of Artificial Dynamic ON or OFF Stimuli to Inhibit Myopia Development

Wang M, Aleman AC, Schaeffel F

Invest Ophthalmol Vis Sci. 2019 Jun 3;60(7):2599-2611

Demyelination and shrinkage of axons in the retinal nerve fiber layer in chickens developing deprivation myopia

Swiatczak B, Feldkaemper M, Schraermeyer U, Schaeffel F

Exp Eye Res. 2019 Nov;188:107783

Click here for a complete list of Frank Schaeffel's publications on PubMed 

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