Single cell technologies enable the analysis of thousands of single cells in just one experiment, generating an unprecedented amount of data. The field is rapidly expanding, with new methods and algorithms for data analysis being published almost every week.

IOB has a state-of-the-art Single Cell Genomics Facility that provides clinicians and basic researchers with guidance, support and advice for implementing single cell sequencing technologies in their current and future projects. Our platform also develops new single cell methods to improve data quality, increase throughput and reduce costs. 

The Single Cell Genomics Facility offers the latest technologies in the Genomics field and has made significant contributions to understanding fundamental molecular mechanisms in healthy and diseased individuals.

To explore collaboration opportunities or to learn more about our platform services, please reach out to us at: single_cell_service@iob.ch

Single Cell and Nuclei Dissociation

Qiagen RNA extraction Kits

Miltenyi Biosciences Tissue Dissociation Kits

Salty-EZ-based protocols (Adapted from Martelotto, LG 2021)

Technologies

10x Genomics Single Cell Gene Expression 3’ and 5’ (with Feature Barcoding and Sample Multiplexing)

10x Genomics Single Cell Multiome

FLASH-seq (plate format only)

G&T-seq (plate format only)

PATCH-seq

Bulk FLASH-seq

Curio Biosciences Seeker (Spatial Transcriptomics)